Description

A pyrimidone resulting from the formal oxidation of the alcoholic hydroxy group of 5-hydroxymethyluracil to the corresponding aldehyde. It is a major one-electron photooxidation product of thymine in oligodeoxynucleotides.

Chemical properties

Chemical formula Net charge Average mass
C5H4N2O3 0 140.097
5-formyluracil

Recommended notation

Name 5-formyluracil
Abbreviation 5fU
Symbol e

Nomenclature

IUPAC SMILES Synonyms
2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde N1C(NC=C(C1=O)C=O)=O
  • fou
  • 5fu
  • uracil 5-carbaldehyde

Mapping techniques

Method Method detail Resolution Enrichment or limitation References
Hardisty-labelling chemical tagging single-base target sequences

Nature

Origin Function Functional detail Organisms References
natural damage and demethylation intermediate Homo sapiens