Description

A primary alcohol that is uracil bearing a hydroxymethyl substituent at the 5-position.

Chemical properties

Chemical formula Net charge Average mass
C5H6N2O3 0 142.11282
5-hydroxymethyluracil

Recommended notation

Name 5-hydroxymethyluracil
Abbreviation 5hmU
Symbol g

Nomenclature

IUPAC SMILES Synonyms
5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione OCc1c[nH]c(=O)[nH]c1=O
  • 5-(hydroxymethyl)uracil
  • 5-hydroxymethyl uracil
  • 5-(hydroxymethyl)-2,4(1h,3h)-pyrimidinedione

Mapping techniques

Method Method detail Resolution Enrichment or limitation References
Hardisty-labelling chemical tagging single-base target sequences
SMRT direct detection single-base target sequences
Yu-labelling chemical tagging single-base 5hmU:G mismatch only

Nature

Origin Function Functional detail Organisms References
natural damage, demethylation intermediate, and possible epigenetic mark
  • Gyrodinium cohnii
  • Homo sapiens
  • Mus musculus
  • Rattus norvegicus