Description

An oxopurine that is guanine which is substituted by an oxo group at position 8.

Chemical properties

Chemical formula Net charge Average mass
C5H3N5O2 0 165.10960
8-oxoguanine

Recommended notation

Name 8-oxoguanine
Abbreviation 8oxoG
Symbol o

Nomenclature

IUPAC SMILES
2-amino-1H-purine-6,8-dione Nc1nc2=NC(=O)N=c2c(=O)[nH]1

Mapping techniques

Method Method detail Resolution Enrichment or limitation References
SMRT direct detection single-base target sequences
array-based profiling affinity-based low target sequences
fluorescence in situ hybridization affinity-based low target sequences
gap ligation excision repair enzymeā€“based high target sequences
immunoprecipitation affinity-based low target sequences
nanopore direct detection single-base target sequences

Nature

Origin Function Functional detail Organisms References
natural damage and possible epigenetic mark reactive oxygen species Homo sapiens