Description

A pyrimidone that is uracil which is substituted at positions 1, 5 and 6 by ethoxymethyl, isopropyl, and benzyl groups, respectively. A non-nucleoside inhibitor of HIV-1 reverse transcriptase, emivirine was an unsuccessful experimental agent for the treatment of HIV.

Chemical properties

Chemical formula Net charge Average mass
C17H22N2O3 0 302.36820
emivirine

Nomenclature

IUPAC SMILES Synonyms
6-benzyl-1-(ethoxymethyl)-5-(propan-2-yl)pyrimidine-2,4(1H,3H)-dione CCOCn1c(Cc2ccccc2)c(C(C)C)c(=O)[nH]c1=O
  • 6-benzyl-1-(ethoxymethyl)-5-(1-methylethyl)uracil
  • 6-benzyl-1-ethoxymethyl-5-isopropyl uracil
  • coactinon
  • 1-(ethoxymethyl)-5-(1-methylethyl)-6-(phenylmethyl)pyrimidine-2,4(1h,3h)-dione
  • mkc-442