Description

A member of the class of pyrimidones that is uracil substituted by chloro and (2-iminopyrrolidin-1-yl)methyl groups at positions 5 and 6 respectively. Used (as the hydrochloride salt) in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer.

Chemical properties

Chemical formula Net charge Average mass
C9H11ClN4O2 0 242.663
tipiracil

Nomenclature

IUPAC SMILES
5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione C1(=C(C(NC(N1)=O)=O)Cl)CN2C(CCC2)=N