Hoffman research group
- Michael M. Hoffman
- Senior Scientist (principal investigator)
- Research
- Princess Margaret Cancer Centre
- University Health Network
- Associate Professor (status-only)
- Computational Biology Group
- Department of Computer Science
- University of Toronto
We develop machine learning techniques to better understand chromatin biology. These models and algorithms transform high-dimensional functional genomics data into interpretable patterns and lead to new biological insight.
Publications
Software
- Segway: semi-automated genomic annotation
- Segtools: segmentation analysis and graphics
- Genomedata: efficient storage and retrieval
- Umap and Bismap: tools for quantifying mappability of the genome and methylome
- BEHST: biological enrichment of hidden sequence targets
- Virchip: predicting transcription factor binding by learning from the transcriptome
- PeaKO: finding transcription factor binding motifs using knockout controls
Databases
- DNAmod: the DNA modification database
Join the lab
People
Meet the team- Michael Hoffman
- Eric Roberts
- Coby Viner
- Mehran Karimzadeh
- Jai Sood
- Mickael Mendez
- Rachel Chan
- Danielle Denisko
- Francis Nguyen
- Samantha Wilson
- Matthew McNeil
- Yi Nian (Jeffrey) Niu
- Siddharth Reed
- Yushan (Ida) Liu
- Michael Wrana
- Natalia Mukhina
News
- 2020-09-04: Michael is promoted to Senior Scientist at the Princess Margaret Cancer Centre, Toronto ON, Canada.
- 2020-09-04: Michael is a member of the Centre for Machine Learning in Medicine, University of Toronto.
- 2020-09-02: Eric releases Segway 3.0.2.
- 2020-08-24: Zhiyuan (Annie) Lu was awarded the Mitacs Research Training Award (RTA).
- 2020-08-16: Michael is an invited speaker to present at CANSSI Ontario: International Data Science Speaker Series at the University of Toronto, December 2020.
- 2020-08-13: Coby was awarded a Canada Graduate Scholarships Michael Smith Foreign Study Supplement.
- News archive
Contact
- Twitter: @michaelhoffman
- LinkedIn: michaelmhoffman