Description
A purine 2'-deoxyribonucleoside that is inosine in which the hydroxy group at position 2' is replaced by a hydrogen.
Chemical properties
| Chemical formula | Net charge | Average mass |
|---|---|---|
| C10H12N4O4 | 0 | 252.22684 |
Recommended notation
| Name | 2'-deoxyinosine |
|---|---|
| Abbreviation | dI |
Nomenclature
| IUPAC | SMILES | InChI | InChIKey | Synonyms |
|---|---|---|---|---|
| 2'-deoxyinosine, 9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-9H-purin-6-ol | OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2c1nc[nH]c2=O | InChI=1S/C10H12N4O4/c15-2-6-5(16)1-7(18-6)14-4-13-8-9(14)11-3-12-10(8)17/h3-7,15-16H,1-2H2,(H,11,12,17)/t5-,6+,7+/m0/s1 | VGONTNSXDCQUGY-RRKCRQDMSA-N |
|
Nature
| Origin | Function | Functional detail |
Organisms
|
References |
|---|---|---|---|---|
| natural | damage and hypermodified nucleobase |
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Citations
- Ehrlich, M, et al. 1985. DNA methylation in thermophilic bacteria: N4-methylcytosine, 5-methylcytosine, and N6-methyladenine. Nucleic Acids Research. 13(4).
- Nguyen, T, et al. 1992. DNA damage and mutation in human cells exposed to nitric oxide in vitro. Proceedings of the National Academy of Sciences of the United States of America. 89(7).
- Saparbaev, M, et al. 1994. Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases. Proceedings of the National Academy of Sciences of the United States of America. 91(13).
- Song, W, et al. 2013. Characterization of nucleobases and nucleosides in the fruit of Alpinia oxyphylla collected from different cultivation regions. Drug Testing and Analysis. 6(3).
- Zhu, Y, et al. 2013. Fecal metabonomic study of a polysaccharide, MDG-1 from Ophiopogon japonicus on diabetic mice based on gas chromatography/time-of-flight mass spectrometry (GC TOF/MS). Molecular BioSystems. 10(2).