Description
A benzyl ether that consists of acyclouridine bearing a 3-(benzyloxy)benzyl substituent at position 5.
Chemical properties
| Chemical formula | Net charge | Average mass |
|---|---|---|
| C21H22N2O5 | 0 | 382.40980 |
Nomenclature
| IUPAC | SMILES | InChI | InChIKey | Synonyms |
|---|---|---|---|---|
| 5-[3-(benzyloxy)benzyl]-1-[(2-hydroxyethoxy)methyl]pyrimidine-2,4(1H,3H)-dione | OCCOCn1cc(Cc2cccc(OCc3ccccc3)c2)c(=O)[nH]c1=O | InChI=1S/C21H22N2O5/c24-9-10-27-15-23-13-18(20(25)22-21(23)26)11-17-7-4-8-19(12-17)28-14-16-5-2-1-3-6-16/h1-8,12-13,24H,9-11,14-15H2,(H,22,25,26) | CSXNPJKDZKLDET-UHFFFAOYSA-N |
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Citations
- Chu, MY, et al. 1984. Potentiation of 5-fluoro-2'-deoxyuridine antineoplastic activity by the uridine phosphorylase inhibitors benzylacyclouridine and benzyloxybenzylacyclouridine. Cancer Research. 44(5).
- Lee, KH, et al. 1984. Inhibition of nucleoside transport in murine lymphoma L5178Y cells and human erythrocytes by the uridine phosphorylase inhibitors 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine. Cancer Research. 44(9).
- Niedzwicki, JG, et al. 1982. 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine, potent inhibitors of uridine phosphorylase. Biochemical Pharmacology. 31(10).