Description

An oxopurine that is guanine which is substituted by an oxo group at position 8.

Chemical properties

Chemical formula Net charge Average mass
C5H3N5O2 0 165.10960
8-oxoguanine

Recommended notation

Name 8-oxoguanine
Abbreviation 8oxoG
Symbol o

Nomenclature

IUPAC SMILES InChI InChIKey
2-amino-1H-purine-6,8-dione Nc1nc2=NC(=O)N=c2c(=O)[nH]1 InChI=1S/C5H3N5O2/c6-4-8-2-1(3(11)10-4)7-5(12)9-2/h(H3,6,8,9,10,11,12) UBKVUFQGVWHZIR-UHFFFAOYSA-N

Mapping techniques

Method Method detail Resolution
Qualifier
References
SMRT direct detection single-base target sequences
array-based profiling affinity-based low target sequences
fluorescence in situ hybridization affinity-based low target sequences
gap ligation excision repair enzyme–based high target sequences
immunoprecipitation affinity-based low target sequences
nanopore direct detection single-base target sequences

Nature

Origin Function Functional detail
Organisms
References
natural damage and possible epigenetic mark reactive oxygen species Homo sapiens